Antifungal Extracts: Overview, Benefits, and Side Effects

Antifungal extracts are derived from organic sources and are used to combat fungal infections. Generally, these extracts are rich in secondary metabolites with antifungal properties. One of the known examples is the leaf extract of Cassia fistula. It is an ethnomedicinal plant that scientists study for its antifungal activities against different fungal strains. This includes Candida albicans, Aspergillus clavatus, and Aspergillus niger. Overall, if we look at these extracts, they provide a viable alternative to conventional antifungal drugs. Additionally, these extracts offer new avenues for antifungal treatment.

Below, we have covered both aspects of the information part, where you can read in-depth about these extracts. Plus, we have also curated a list of the 4 best antifungal extracts that can help provide many health benefits. Continue reading! 

Overview of Antifungal Plant Extracts 

Antifungal extracts are natural substances that originate from plants and contain antifungal properties. These extracts are obtained from various plant parts, including leaves, seeds, and roots. In addition, they are used to treat fungal infections because they have the ability to inhibit the growth or kill fungi. For instance, the leaf extracts of the Cassia fistula have shown antifungal activity against fungal strains. It includes Aspergillus clavatus, Aspergillus niger, and Candida albicans. 

Similar to the extracts from the leaves and roots of the Avicennia marina (a mangrove plant), they have shown their effectiveness with antifungal and antibacterial activity against many fungal strains and bacteria. Moreover, these natural extracts are often considered more valuable than synthetic antifungal drugs due to fewer side effects and reduced drug resistance. It is because they have the potential to overcome drug resistance. Also, reduce the side effects linked with conventional treatments.

Benefits of Using Antifungal Extracts 

These extracts provide potential benefits as natural remedies for fungal infections. They act as a chemical-free alternative for treatment and food preservation. Moreover, they can help prevent fungal growth and offer a sustainable approach to combat fungal infections.

Here, we have explained the benefits of these extracts: 

Natural and Chemical-Free 

Antifungal plant extracts come from plants that offer a natural and chemical-free option compared to synthetic antifungal medications. 

Prevent Fungal Growth 

These extracts can prevent the growth of several fungal species. This includes those causing hair, skin, and nail infections.

Breaks Down Fungal Walls

Several extracts target fungal cell walls, leading to cell death and preventing infection.

Preserves Food

These extracts can be used to prevent fungal spoilage in food, which helps extend the shelf life and reduce food waste.

Good for Skin

Plant extracts used in skincare products can provide many benefits. This includes antioxidant activity, UV protection, and antimicrobial activity.

Possible Side Effects of Antifungal Extracts

As we discussed above, these extracts are effective against fungal infections, but they can cause some side effects, too. It depends on the type of extract and its dosage. The common side effects include nausea, mild skin irritation, diarrhea, and abdominal pain. In some cases, serious liver-related side effects may occur.

Below, we have created a detailed breakdown of the potential side effects: 

Common Side Effects

• Skin Irritation: Topical liquids and antifungal creams may cause a little irritation, stinging, burning, itching, redness, or rash where you have applied them.

• Gastrointestinal Issues: If you are consuming oral antifungal, it can lead to vomiting, nausea, diarrhea, abdominal pain, and indigestion. 

• Headache: There are some antifungal medications, such as fluconazole, that can cause headaches.

• Taste Disturbances: For example, Terbinafine can cause disturbances with the taste. 

• Muscle or Joint Pain: Terbinafine can also cause joint or muscle pain. 

• Allergic Reactions: In rare cases, antifungal medications can lead to allergic reactions. This may include swelling of the neck, face, or tongue and difficulty breathing.

• Rash: Some antifungal medications can cause a rash. 

Serious Side Effects

• Liver Damage: Certain antifungal medications, specifically itraconazole and ketoconazole, can cause liver damage, but in rare cases. 

• Renal Toxicity: Amphotericin B, known to be a powerful antifungal, can cause problems with the kidneys. 

• Hormone-Related Issues: If you use the azole antifungals for a long period of time, it can cause hormone-related effects, such as adrenal insufficiency, hyponatremia, and hypokalemia.

• Peripheral Neuropathies: Posaconazole and Voriconazole have been linked with peripheral neuropathies.

• Pancreatitis: Voriconazole and Itraconazole have been connected with pancreatitis. 

• Severe Skin Reactions: In rare cases, the consumption of oral antifungal drugs can lead to severe skin reactions, such as blistering or peeling skin.

Also Read:- Barberry Root Tincture: Benefits, Side Effects, and More!

Important Things to Consider

• Antifungal Type: The type of antifungal medication, for example, oral tablet, topical cream, or injection, and the specific active ingredient, will cause potential side effects. 

• Dosage: If you are taking higher doses of antifungal medications, this may increase the risk of side effects. 

• Sensitivity of an Individual: People may react differently to antifungal medications. Some are more sensitive to specific side effects. 

• Treatment Duration: The longer the course of treatment is with the antifungal medications, the higher the chance of side effects. 

• Previous Medical Conditions: Those with kidney or liver problems may be at a higher risk of facing side effects from antifungal medicines. 

• Drug Interactions: There is a chance that antifungal medications can interact with other medicines. So, it is essential to inform the doctor about your history of medication and what you are currently taking. 

• Talk to a Healthcare Provider: If you are facing any of the side effects while taking the antifungal medications, it's crucial to contact your doctor as soon as possible.

Shop Effective Antifungal Extracts at Shea’s Apothecary 

If you are looking to add these extracts to improve your daily routine, you are at the right place. Below, we have discussed Shea's Apothecary's top 4 extracts that can help improve your overall well-being. Each one of the extracts offers a unique benefit to support your vibrant lifestyle.

1. Calendula Tincture

Calendula is also called garden marigold or pot marigold. It is a plant in the family of daisies (Asteraceae) with a history of culinary and medicinal uses. Additionally, it is known for its bright orange or yellow flowers and is traditionally used to treat various skin conditions. Traditionally, it was used to promote wound healing and skin conditions, prevent infections, and more. 

Moreover, it has the ability to improve the skin's appearance, boost the immune system, stimulate healing, and detoxify the body. Calendula has a mild taste that can be slightly salty, sweet, or bitter, depending on the preparation. How can you use Calendula? There are various ways in which you can use it, including tea, infusion, food, lotion, powder, and more.

2. Coriander Extract Tincture

Coriander (Coriandrum sativum L.) has shown antifungal properties, specifically against Candida species. According to the studies, coriander essential oil can stop the growth of Candida strains. It has shown varying levels of effectiveness against C. albicans and C. tropicalis. Moreover, coriander is historically used to alleviate digestive issues and combat inflammation. One of the best uses of coriander is that it helps in digestion. It is also an aromatic carminative used to treat colic, gas, and intestinal cramps. As per Ayurveda, coriander is especially indicated in pitta-type digestive conditions. Additionally, when consumed, you will experience a pungent, bitter, and spicy taste.

3. Burdock Root Tincture

Burdock is also called Arctium lappa, and it is known to be a powerful herb that has been used for centuries to provide many health benefits. In addition, this herb is specifically known for its ability to help break down toxins, as well as its blood-purifying qualities and metabolic waste in the body. Also, it is a great support for conditions like hypertension, cancers, digestive ulcers, gout, and reproductive problems. It has amazing healing properties and is a must-have herb for those looking to have something to support their overall wellness. 

Burdock root also contains many nutrients like vitamins A, C, D, E, K, and beta carotene. It also contains minerals like calcium, iron, potassium, magnesium, phosphorus, zinc, selenium, and more. Additionally, it is rich in fiber, which helps to fight infection and lowers cholesterol levels. The Burdock root tastes sweet and bitter (mildly bitter on the side) and has a slightly sweet flavor. 

4. Cardamom Extract Tincture

Cardamom is very well-known for reducing uncomfortable bloating and embarrassing acidity. Plus, it regulates the digestive system. Additionally, it contains a compound known as methanolic extract. It is known to be an antioxidant that provides relief from flatulence and stomach cramps and even helps with stomach ulcers.

You will get to experience many health benefits from cardamom. It includes cholesterol control, gastrointestinal protection, relief from cardiovascular issues, control of cancer, and improved blood circulation in the body. Additionally, it is used for urinary tract issues like nephritis and cystitis, and may also support treatment for conditions such as gonorrhea. The taste of cardamom is sweet and pungent. 

In Closure 

Antifungal extracts help treat the fungal infections that affect the nails, skin, and other organs. Some of the fungal infections clear up in a few weeks, but others may need months of treatment. Taking antifungal medications for extended periods or failing to complete the prescribed course may lead to resistance. So, it is better that you complete the course or talk to your healthcare professional if you face any problems.

Are you looking for an ideal place to buy products like antifungal extracts? Look no further than Shea's Apothecary. We provide a diverse range of the most effective herbal products to our customers. Explore our collection of extracts, like Calendula, Coriander, Burdock Root, and more. Shop now and enjoy great discounts on our herbal products!

Frequently Asked Questions 

How Long Do the Extracts Remain Potent After Opening?

The herbal extracts usually remain fully potent for around 2 years after the date of manufacturing. However, it must be noted that the effectiveness of the medicine can decrease with time. If you want to maintain its potency, you have to store it properly.

Can I Use Antifungal Extracts for Pets?

Yes, you can use extracts for pets, but it is crucial to consult a veterinarian. Make sure that you are providing the correct diagnosis and the right treatment plan. For dogs and cats suffering from fungal infections, antifungal creams can be used for treatment. But they are not usually recommended for widespread infections. 

How Long Does It Take to Develop a New Antifungal Drug? 

The development of a new antifungal drug generally takes around 10 to 15 years on average. It also includes the discovery of the drug and the preclinical and clinical development phases.